PRKN and Sepsis: Sepsis and renal‐I/R‐induced AKI activates mitophagy by increasing PINK1 and PARK2 protein levels (Tang et al., 2018; Wang, Wang, et al., 2020; Wang et al., 2021), whereas genetic ablation of PINK1 and/or PARK2 exacerbates renal I/R or sepsis‐induced AKI (Tang et al., 2018; Wang et al., 2021).