Likewise, the beneficial effects of ischemia preconditioning and annexin A1 tripeptide against renal I/R‐induced AKI (Suliman et al., 2021; Wang, Zhu, Li, Ren, & Zhou, 2020) and heat shock protein‐27 (HSP‐27) against cardiac cell death (Kang et al., 2011; Lin et al., 2016) are mediated in part by PINK1‐PARK2‐dependent mitophagy. This evidence concerns the gene PINK1 and acute kidney injury.