Interestingly, increased circulating levels of IL‐18 have been found in patients with decreased skeletal muscle mass, including sarcopenia, heart failure, and chronic obstructive pulmonary disease (COPD) (Imaoka et al., 2008; Li et al., 2019; Petersen et al., 2007; Seta et al., 2000). This evidence concerns the gene IL18 and sarcopenia.