<h4>Purpose</h4>To report on a case of successful treatment of intraocular inflammation (IOI) secondary to brolucizumab intravitreal injection that responded to a single sub-Tenon injection of triamcinolone.<h4>Observations</h4>An 81-year-old female with a longstanding history of exudative age-related macular degeneration (AMD) was unresponsive to various regimens of <i>anti</i>-VEGF injections. Here, VEGFA is linked to age-related macular degeneration.