Compared with the sepsis serum group, the mRNA levels of VCAM-1 (1.00 ± 0.03 vs. 0.36 ± 0.01, p < 0.05, Figure 5C) and ICAM-1 (1.00 ± 0.06 vs. 0.37 ± 0.01, p < 0.05, Figure 5E) were significantly reduced after treatment with M8I. This evidence concerns the gene ICAM1 and Sepsis.