MALAT1 and hepatocellular carcinoma: Malakar et al. (61) found that MALAT1 enhances the translation of metabolic transcription factor TCF7L2 by upregulating shear factor SRSF1 and activating the mTORC1-4EBP1 axis to upregulate glycolysis genes and inhibit gluconeogenesis, promoting the development of HCC (62).