Most genes were characterised by copy number amplification, including FADS2, FTH1, NQO1, ABCC1, AKRIC2, AKRIC1, FANCD2, and AKR1C3, whereas some genes including ACSL3, GOT1, FDFT1, HMGCR, GPX4, and CRYAB were characterised by copy number deletion in bladder cancer. This evidence concerns the gene GPX4 and urinary bladder cancer.