ACSL3 and neoplasm: Furthermore, ferroptosis-related genes with copy number amplification (including FADS2, NQO1, ABCC1, ACSF2, HMOX1, FANCD2 and SQLE) demonstrated higher expression in tumour tissues, and those with copy number deletion (including CRYAB, ACSL3, ZEB1) demonstrated lower expression in tumour tissues.