Mean CSF NLRP3 (ng/ml) was 2,124 ± 1,396 for S. pneumoniae infection, 2,606 ± 1,497 for K. pneumoniae infection, 2,181 ± 2,386 for E. coli infection, and 1,213 ± 996.9 for L. monocytogenes infection. The gene discussed is NLRP3; the disease is escherichia coli infection.