BRCA1 and breast cancer: Although the specific etiology of BC is unknown, risk factors have been recognized [4], such as female gender [2], aging, a family history of BC, particular abnormalities in the breast(s) [4], mutations in the breast cancer gene 1 (BRCA1), breast cancer gene 2 (BRCA2), and partner and localizer of BRCA2 (PALB-2), reproductive history (such as the age at which menstrual periods began and the age at which the first pregnancy occurred), cigarette use, postmenopausal hormone treatment factors [2], lack of physical activity, alcohol intake, obesity, diet, race, and chest radiation therapy [4].