CWC: cirrhosis with COVID-19; CWOC: cirrhosis without COVID-19; COVID-19: coronavirus disease 2019; CLD: chronic liver disease; HBV: hepatitis B virus; NASH: non-alcoholic steatohepatitis; AIH: autoimmune hepatitis; HCV: hepatitis C virus; EHPVO: extrahepatic portal venous obstruction; BCS: Budd-Chiari syndrome; AD: acute decompensation; ACLF: acute on chronic liver failure; TLC: total leucocyte count; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic pyruvic transaminase; INR: international normalized ratio; CTP: Child-Turcotte-Pugh; MELD: Model for End-Stage Liver Disease. The gene discussed is GOT1; the disease is acute-on-chronic liver failure.