Additionally, TIM including CD3+, CD4+, CD8+, CD20+, CD68+, Foxp3+CD4+ TILs infiltrations in different tumor regions and immune-related genomic alterations and gene expression of HPV(+)OPSCC stratified by PD-L1 CPS were also described using a cohort of 112 HPV(+)OPSCC cases in our institute from 2008–2021. Here, CD274 is linked to neoplasm.