Our previous study found that the abundance of CCL2 and CCR2 in the renal tubules of rats with contrast-induced nephropathy (CIN) increased, accompanied by an increase in the concentration of IL-6 and TNF-α in the kidney and serum, and TMP could inhibit the CCL2/CCR2 pathway activation (Gong et al., 2019). Here, TNF is linked to cervical squamous intraepithelial neoplasia.