Lastly, in healthy older adults (>65 years), caudate atrophy was related to gait speed (Dumurgier et al., 2012) and striatal dopamine denervation in the caudate, as measured by [11C]-β-CFT dopamine transporter PET imaging, was related to reductions in cadence and gait speed (Bhatia and Marsden, 1994). The gene discussed is SLC6A3; the disease is Caudate atrophy.