Interestingly, when we utilized FTY720, a sphingosine 1-phosphate (S1P) receptor agonist, to block the egress of lymphocytes from lymphoid organs (Supplementary Fig. S4E), we found that the inhibition of IFNα-MSCs on tumor growth were dramatically impaired (Fig. 4J). This evidence concerns the gene IFNA1 and neoplasm.