Given that an inversed relation between the tumor weight and CD8+ T cell infiltration and a dramatic downregulation of Cxcl10 in melanoma at the late stage (Fig. 5C, D), we tested if addition of IFNα or IFNα-MSCs could enhance the expression of CXCL10 in B16F0 cells. This evidence concerns the gene CXCL10 and melanoma.