The finding that BRAFV600E mice displayed adenomas (Fig. 2A–C) staining positive for the prosurfactant protein C (SPC), a marker of alveolar type II cells (ATIIs), and negative for CC10, a protein specifically expressed by Club cells (CCs), confirmed the evidence that BRAFV600E-induced adenomas display the properties of ATIIs [9, 17] (Fig. 3A, B). The gene discussed is SCGB1A1; the disease is adenoma.