CASP8 and acute respiratory distress syndrome: Indeed, our results showed a significant higher levels of caspase 3 (∼35 Kda), cleaved caspase 3 (∼17 Kda), cleaved caspase 8 (∼20 Kda), and caspase 9 (∼46 Kda), and in the lung of ARDS-developing mice compared to HP-developing mice (Fig. 2A–E).