Under the surviving stress upon TKIs, elevated METTL7B in LUAD cells accelerated the scavenging of excessive ROS in tumor microenvironment by upregulating the protein levels and enzymatic activities of three antioxidant enzymes GPX4, SOD1 and HMOX1 by m6A modification in their mRNAs (Fig. 8h). Here, GPX4 is linked to neoplasm.