APOA5 and hypertriglyceridemia: A previous genome wide association study (GWAS) proved that several single nucleotide polymorphisms (SNPs) associated with hypertriglyceridemia in normolipidemic samples, including SNPs in the genes of APOA5, TRIB1, TBL2, GCKR, GALNT2 and ANGPTL3, were significantly associated with hyperlipoproteinemia Fredrickson types 2B, 3, 4 and 5 [56].