Non-COVID non-ARDS lungs (Patient 9,16 and 19, see Table 1) showed significantly lower NLRP3 and caspase 1 expressions as compared to the two other cohorts (COVID-19 ARDS and non-COVID-19 ARDS) (Figs. 3A, B lower two panels and Fig. 3C). This evidence concerns the gene CASP1 and acute respiratory distress syndrome.