Two patients received treatment: the patient with the well-differentiated colonic NEN (well-differentiated but Ki67 60%, not small-cell or large-cell) was completely resected, did not receive adjuvant therapy, and remains disease free four years later; the patient with the duodenal NEN (pT1N0M0, Ki67 2%) had cold biopsy polypectomy, and remains cancer-free at four months. Here, MKI67 is linked to cancer.