IL17A and rheumatoid arthritis: While numbers of IL-17–producing γδ T cells in the feet were negligible, we found that neutrophils as well as MHC-II+ve myeloid cells also expressed IL-17 in the feet during peak RRV disease, corroborating previous reports that neutrophils can contribute IL-17 in RA [77], and pointing to the possibility that synovial macrophages could be contributing to this signal in an highly inflamed environment, as has been shown in other disease models [78,79].