Significant upregulation of TRIM16, TRIM24, and TRIM28 in HCC tissue was detected with high staining and strong intensity by the HPA, consistent with assessment at the transcriptional level in the TCGA and GTEx databases (p = 5.7E‐30, p = 7.6E‐35, and p = 5.9E‐49, respectively) (Figure 3C–E,N–P). The gene discussed is TRIM28; the disease is hepatocellular carcinoma.