Significant upregulation of TRIM16, TRIM24, and TRIM28 in HCC tissue was detected with high staining and strong intensity by the HPA, consistent with assessment at the transcriptional level in the TCGA and GTEx databases (p = 5.7E‐30, p = 7.6E‐35, and p = 5.9E‐49, respectively) (Figure 3C–E,N–P). Here, TRIM16 is linked to hepatocellular carcinoma.