An important clinical feature of autoimmune diseases is the disorder of inflammatory factors, such as serum amyloid A (SAA), C‐reactive protein (CRP), albumin (ALB), erythrocyte sedimentation rate (ESR), and neutrophil‐to‐lymphocyte ratio,8, 9 which have been proved to be related with the severity and prognosis of the disease, and the predictive value of different indicators are different. The gene discussed is ALB; the disease is autoimmune disease.