KEGG enrichment analysis of the 17 miRNAs revealed that these miRNAs were involved in multiple pathways related to HCC, such as the Hippo (Liu et al., 2020b), FoxO (Hou et al., 2016), TGF-beta (Mazzocca et al., 2012), PI3K-Akt (Zhou, 2011), and Wnt (Pez et al., 2013) signaling pathways. This evidence concerns the gene AKT1 and hepatocellular carcinoma.