The basic data of patients with thoracic trauma in different conditions were analyzed, and the results showed that there were differences between patients with combined ARDS and those without combined ARDS in long-term smoking, nature of injury, massive blood transfusion, APACHE II score, ISS score, CRP, PCT, IL-6, TNF-α, etc. (P < 0.05). This evidence concerns the gene TNF and acute respiratory distress syndrome.