IL1B and Granuloma: Enrichment analysis with GO analysis revealed that various biological pathways were enriched such as “Cellular response to IL-1,” “Cellular response to IFN-γ,” “Positive regulation of IL-6,” “IL-8 secretion,” “Mononuclear cell migration,” “Regulation of mononuclear cell migration,” and “Response to lipopolysaccharide (LPS),” all of which are reported to be in relation to granuloma formation in sarcoidosis lesion (Table 2A).