For the eighth patient, 6052, who was diagnosed with a homozygous recessive variant in TANGO2 (OMIM#616878; Metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration) the Delphi panel failed to reach consensus on whether a molecular diagnosis likely reduced the length of hospital stay for a metabolic crisis. Here, TANGO2 is linked to chronic obstructive pulmonary disease.