According to the literature search results, higher CXCL13 expression was found in colorectal cancer (13), renal cell carcinoma (14), hepatocellular carcinoma (15), gastric cancer (16), breast cancer (17, 18), lung cancer (19), pancreatic adenocarcinoma (20), cutaneous melanoma (21) and leukemia (22), which were consistent with our study. This evidence concerns the gene CXCL13 and hereditary clear cell renal cell carcinoma.