According to the literature search results, higher CXCL13 expression was found in colorectal cancer (13), renal cell carcinoma (14), hepatocellular carcinoma (15), gastric cancer (16), breast cancer (17, 18), lung cancer (19), pancreatic adenocarcinoma (20), cutaneous melanoma (21) and leukemia (22), which were consistent with our study. The gene discussed is CXCL13; the disease is colorectal cancer.