TRPC1 and cancer: Finally, given the demonstrated specificity of PEMF treatment for TRPC1 expression reported here and elsewhere (5, 11, 32, 45), complementation of conventional DOX-based chemotherapy by localizable PEMF exposure may serve as a method to avert collateral toxicity (3) as well as paradoxical effects (57), by allowing the lowering of dose systemically-delivered chemotherapeutic drug while maintaining a unique level of specificity for TRPC1-associated cancers.