In SS animal experiments, immunization of wild-type C57BL/6 mice with salivary gland protein can induce obvious SS symptoms, accompanied by an increase in cervical lymph node Th17 cells, salivary gland inflammation, and lymphocyte infiltration, while there are no SS symptoms and histopathological changes in IL-17A knockout mice [22]. The gene discussed is IL17A; the disease is synovial sarcoma.