We observed 10% probability of insulin resistance occurrence at an SHBG concentration of 111.1 nmol/L, 20% at 85.3 nmol/L, 25% at 76.1 nmol/L, 33.3% at 63.2 nmol/L, and 50% at 41.1 nmol/L, while the probability of IR for an SHBG concentration of 26.1 nmol/L was 61.6% (95% CI: 57.4–65.8). This evidence concerns the gene SHBG and Insulin resistance.