Moreover, we found several important shared mRNAs between ceRNA networks of COAD and READ (CRC, cancer cluster 3:CC-3) (Table 2), which included APC, EDIL3, FGFR2, HOMER1, MIER3, PI15, RBM28, RRS1, SCML1, SGPP1, TOMM34, TRAF5, WNT5A, and ZNF655. For other cancer clusters, other important shared mRNAs as shown in Table 2 were identified. This evidence concerns the gene PI15 and cancer.