Thus, the present study indicates that the SNPs reported in the GWAS meta-analysis of chronic back pain (SOX5 rs34616559, CCDC26/GSDMC rs7833174 and DCC rs4384683) are not of prognostic value in a clinical setting for subjects admitted to a secondary health care institution for an acute episode of LBP with radiculopathy. This evidence concerns the gene GSDMC and radiculopathy.