described the mechanism by which decitabine enhanced the expression of immune-related genes such as major histocompatibility complex genes and cytokine-related genes in a syngeneic mouse CT26 colon cancer model and found an increased accumulation of cytolytic CD8+ T cells in the tumor, demonstrating the sensitizing effect of decitabine against PD-1 antibody therapy (127). Here, CD8A is linked to neoplasm.