Figure 5B indicated that Type II diabetes mellitus, Insulin resistance, Fc gamma R-mediated phagocytosis, Inflammatory mediator regulation of TRP channels and other signaling pathway were enriched. Protein kinase C-epsilon (PRKCE) was involved in all above pathways and corresponding lncRNA was ENST00000462720 and ENST00000480633. All enriched signaling pathways of PRKCE were shown in Tables S3 and S5. This evidence concerns the gene PRKCE and Insulin resistance.