Additionally, the high expression of ANGPTL4 in the ovarian granulosa cells might be an independent predictor in PCOS (OR: 3.345; 95% CI: 1.951–5.734) with a close contact with incidence of PCOS (AUC: 0.704; 95% CI: 0.633–0.774, p < 0.001). This evidence concerns the gene ANGPTL4 and polycystic ovary syndrome.