Studies have shown that CRP directly involved in endothelial dysfunction in patients with high blood pressure, the development of vascular sclerosis and blood pressure, and CRP indicators can serve as a biomarker associated with atherosclerosis, vascular stiffness, end-organ injury, and the development of cardiovascular events (Hage, 2014; Zhang J. et al., 2019). The gene discussed is CRP; the disease is atherosclerosis.