Finerenone exerts its renal protective effects in patients with T2D and CKD mainly by reducing inflammation, fibrosis, and albuminuria (Chaudhuri et al., 2021; Wang et al., 2021), while the renoprotective mechanisms of SGLT2 inhibitors also include these (Chaudhuri et al., 2021; Wang et al., 2021). This evidence concerns the gene SLC5A2 and chronic kidney disease.