AICDA and cancer: Notably, our analysis revealed omikli due to tobacco smoking (SBS4), clock-like mutational processes (SBS5), ultraviolet light (SBS7), both direct and indirect mutations from AID (SBS9 and SBS85), and multiple mutational signatures with unknown aetiology in different cancer types (SBS8, SBS12, SBS17a/b, SBS28, SBS40 and SBS41) (Fig. 2).