Through analyzing the clinicopathological features of patients with HCC, we found that high expression of DDR1 was significantly correlated with poor tumor differentiation (P = 0.019), incomplete tumor encapsulation (P = 0.029), advanced tumor TNM stage (P = 0.012), and tumor recurrence (P = 0.001) (Supplementary Table S2). Here, DDR1 is linked to hepatocellular carcinoma.