Pathway analysis showed that the differentially expressed genes upon DDR1 knockdown (Supplementary Fig. S2A) were mainly involved in extracellular matrix structural constituent, proteinaceous extracellular matrix, extracellular matrix, extracellular matrix component, glycosaminoglycan binding and extracellular matrix organization, implying that DDR1 might be involved in tumor invasion and metastasis. The gene discussed is DDR1; the disease is neoplasm.