AKT1 and hypertrophic cardiomyopathy: The up-regulated KEGG pathways found in both analyses included ‘focal adhesion’, ‘PI3K-Akt signaling pathway’ ‘hypertrophic cardiomyopathy’, ‘dilated cardiomyopathy’, ‘ECM-receptor interaction’, ‘vascular smooth muscle contraction’ and ‘oxytocin signaling pathway’ (Fig. 6).