In the CGGA (Chinese Glioma Genome Atlas) dataset with matched RNA-seq and survival data from 325 patients (RRID:SCR_018802- mRNAseq_325 (batch 2)- http://www.cgga.org.cn/download?file=download/20200506/CGGA.mRNAseq_325.RSEM-genes.20200506.txt.zip&type=mRNAseq_325&time=20200506), gene signatures for MC3–MC6 was associated with significantly worse overall survival (Fig. 4g). The gene discussed is MC3R; the disease is glioma.