Interestingly, the expression of inflammatory cytokine genes such as TNF-α-induced gene G0S245, IL-1B (encoding IL-1β), and TNF-α-induced apoptosis-associated gene IER3 were higher in M6 than in M5, which also expressed the marker genes of cDC2, CD1C, and FCER1A, but they appeared in both thyroid tissues and PBMCs of HT patients (Fig. 8a, c). Here, IER3 is linked to hematocrit.