In an experiment using KPC mice, one group firstly received the CXCR2 inhibitor AZ13381758 100 mg/kg BID for 2 weeks to increase T cell infiltration into the tumor, followed by the administration of anti-PD-1 antibodies (10 mg/kg BIW) while AZ13381758 continued. This evidence concerns the gene PDCD1 and neoplasm.