Specifically, the ability of influenza-specific antibodies to drive Fc ɣ receptor (FCGR)-dependent functions, namely antibody-dependent cellular phagocytosis (ADCP) (Jegaskanda, 2018; Mullarkey et al., 2016), neutrophil production of reactive oxygen species (Mullarkey et al., 2016), antibody-dependent cellular cytotoxicity (Huber et al., 2001), and antibody-dependent complement deposition (ADCD) (Jegaskanda, 2018; Kopf et al., 2002; O'Brien et al., 2011; Rattan et al., 2017), have been linked to protection from influenza infection and disease. This evidence concerns the gene FCGR2A and influenza.