Thus, beyond neutralizing antibody transfer from mother to child in the cord blood of vaccinated mothers (Katz et al., 2018), the data presented here point to a combined FCGR-binding antibody signature, across FCGR2A, FCGR2B, and FCGR3A specific to the infecting subtype of influenza, in vaccine-induced protection from influenza infection. The gene discussed is FCGR3A; the disease is influenza.