Schütten Schütten MT MT Houben Houben AJ AJ Leeuw Leeuw PW PW Stehouwer Stehouwer CD CD The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension Physiology Physiology 2017 2017 32 32 3 3 197 197 209 209 10.1152/physiol.00037.2016. The gene discussed is REN; the disease is obesity due to melanocortin 4 receptor deficiency.