If the number of T cell subsets is calculated per mm2 tissue (defined as entire sample area minus infiltrate area), the numbers of both CD3+CD8+ cytotoxic T cells and CD3+CD8−FoxP3+ regulatory T cells are increased in Q fever AAA (p=0.043 and p=0.036, respectively) (Figure 7I). The gene discussed is CD8A; the disease is triple-A syndrome.