The IBA1 profile in the PD mouse model was assessed by tissue immunofluorescence, which disclosed that 6-OHDA elevated the IBA1-positive cell number in the SN versus the Sham group, whereas knockdown of MIR17HG reduced IBA1-positive cells (P < 0.05,Figure 4a). The gene discussed is MIR17HG; the disease is Parkinson disease.