Some studies demonstrated that IL‐8 was elevated in future BOS patients compared to those who would never develop BOS [27, 39, 40], and correlated with increased BOS risk [39], while Zheng et al. found persistently elevated levels in both future BOS patients and those who would remain stable compared to healthy controls [35]. This evidence concerns the gene CXCL8 and Buschke-Ollendorff syndrome.