TNC and triple-A syndrome: AAA in WT mice had more degraded elastin fibres as well as focal infiltrates of leukocytes compared to TNC KO mice with AAA showing more dilated and less degraded elastin fibres (Fig. 5A–C; WT-AAA: 3.25 ± 0.75, TNC KO-AAA: 2.32 ± 1.15, P < 0.05).