CRP and COVID-19: Older people were more sensitive to SARS-CoV-2 infection and had a higher positive rate than younger individuals.34 Also, older subjects were associated with increased mortality from COVID-19 due to poorer lung function and the likelihood of having comorbidities when compared with younger patients.34,35 Ageing is associated with an increase in pro-inflammatory cytokine levels (CRP, D-dimer, procalcitonin, and IL-10).36 Older patients typically experience a decline in physiological immune function and immunosuppression, thus making it difficult for them to control pro-inflammatory responses.35